Bombesin hydrate acetate salt
Bombesin
CAS: 31362-50-2
Molecular Formula: C71H110N24O18S
Bombesin hydrate acetate salt - Names and Identifiers
Bombesin hydrate acetate salt - Physico-chemical Properties
| Molecular Formula | C71H110N24O18S |
| Molar Mass | 1619.85 |
| Density | 1.50±0.1 g/cm3(Predicted) |
| Solubility | 0.05 M acetic acid: 20mg/mL, clear, colorless |
| Appearance | Powder |
| Merck | 13,1320 |
| BRN | 9611365 |
| pKa | 13.04±0.46(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| In vitro study | Bombesin is a tetradecapeptide with a COOH terminus ending in Gly-His-Leu-Met-NH2 and subsequently is shown to closely resemble two mammalian bombesin -related peptides, gastrin-releasing peptide (GRP) and neuromedin B (NMB). Bombesin is found to have stimulatory effects upon gastric and pancreatic secretions, release of gastrointestinal hormones, gallbladder contraction and bronchoconstriction. It is present in amphibian gastric endocrine cells, avian proventriculus endocrine cells and avian brain. In mammals it is present mainly in nerve cells and fibers. The only mammalian endocrine cell shown to date to have bombesin is the P-cell in fetal lung. Bombesin is also found in mammalian brain, with its highest concentration in the hypothalamus. Bombesin is shown to be a potent mitogen for Swiss 3T3 cells. In the presence of a low concentration (3.5%) of serum, bombesin stimulates 3T3 cell proliferation. In serum-free medium, bombesin induces DNA synthesis in the absence of any other added growth factor (IC 50 =1 nM). |
Bombesin hydrate acetate salt - Risk and Safety
| Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | BD3480000 |
| FLUKA BRAND F CODES | 10 |
Bombesin hydrate acetate salt - References
| biological activity | Bombesin is a tetradecapeptide originally isolated from frog skin; it plays an important role in Gastrin Release and G protein receptor activation. |
Last Update：2024-04-09 21:54:55
Supplier List
Spot supply
Product Name: Bombesin acetate salt hydrate Visit Supplier Webpage Request for quotationCAS: 31362-50-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
Spot supply
Product Name: Bombesin acetate salt hydrate Visit Supplier Webpage Request for quotationCAS: 31362-50-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
View History